Recombinant Human CD209 Protein, Fc Tag

Name: Recombinant Human CD209 Protein, Fc Tag
Brand: KMD Bioscience
SKU: KMH373

KMH373

CDSIGN, CLEC4L, DC SIGN, DC SIGN1, CD209 molecule

DATASHEET MSDS

Product Description

Alias	CDSIGN, CLEC4L, DC SIGN, DC SIGN1, CD209 molecule
Catalog Number	KMH373
Molecular Name	CD209
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	CD molecule
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Human Dendritic Cell-specific ICAM-3 Grabbing Non-integrin (DC-SIGN)/CD29 is a member of the C-type lectin family. The canonical DC-SIGN/CD29 isoform is a 46 kDa, 44 amino acid (aa) type II transmembrane protein. The extracellular region contains a Ca2+-dependent carbohydrate-binding lectin domain. Multiple human DC-SIGN/CD29 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGN/CD29 is not well conserved between mouse and human, with the extracellular domain sharing only 63% aa identity. The DC-SIGN/CD29 lectin domain binds mannose oligosaccharides on pathogens including HIV as well as self glycoproteins including ICAMs. DC-SIGN/CD29 binds to butyrophilin 2A1 and this interaction can be blocked by HIV pp12. DC-SIGN/CD29 is expressed on dendritic cells (DC) and inflammatory macrophages and contributes to antigen presentation.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	63.06 kDa
Note	仅供科研使用

Login