Recombinant Human CD202B/TEK Protein, His Tag
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Product Number
KMH366
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Alias
TIE2, VMCM, GLC3E, TIE 2, VMCM1, CD202B, TEK receptor tyrosine kinase
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Specifications
- 50ug
- 100ug
Product Description
| Alias | TIE2, VMCM, GLC3E, TIE 2, VMCM1, CD202B, TEK receptor tyrosine kinase |
| Catalog Number | KMH366 |
| Molecular Name | TEK |
| Species | Human |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | CD molecule |
| Purity | ≥90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | PBS |
| Background | The molecularweight of the dimer is 25 kDa. The soluble receptor protein consists of thefull extracellular domain (Met1-Val73). TIE-1 (tyrosine kinase with Ig andEGF homology domains 1) and TIE2/TEK comprise a receptor tyrosine kinase(RTK) subfamily with unique structural characteristics: twoimmunoglobulin-like domains flanking three epidermal growth factor (EGF)-likedomains and followed by three fibronectin type III-like repeats in theextracellular region and a split tyrosine kinase domain in the cytoplasmicregion. These receptors are expressed primarily on endothelial andhematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. Human TIE2 cDNA encodes a 1124 amino acidresidue precursor protein with an 18 residue putative signal peptide, a 727residue extracellular domain and a 354 residue cytoplasmic domain. Twoligands, angiopoietin 1 and angiopoietin 2, which bind TIE2 withhigh-affinity have been identified. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Molecular Weight | 81.95 kDa |
| Note | 仅供科研使用 |
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