Recombinant Human CD117/KIT Protein, His Tag

Name: Recombinant Human CD117/KIT Protein, His Tag
Brand: KMD Bioscience
SKU: KMH292

KMH292

PBT, SCFR, C Kit, CD117, MASTC, KIT proto oncogene, receptor tyrosine kinase

DATASHEET MSDS

Product Description

Alias	PBT, SCFR, C Kit, CD117, MASTC, KIT proto oncogene, receptor tyrosine kinase
Catalog Number	KMH292
Molecular Name	KIT
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	CD molecule
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS, pH7.5
Background	Stem cell factor receptor (SC R), also known as c-kit, has a molecular weight of 145 kDa as a mature protein and is a member of the type III receptor tyrosine kinase (RTK) family that includes platelet-derived growth factor (PDGF) receptors and the macrophage colony-stimulating factor 1 (CSF-1) (c-fms) receptor. SCFR is essential for the development of normal hematopoietic cells and plays an important role in the survival, proliferation, and differentiation of mast cells, melanocytes, and germ cells. SCF R contains five extracellular immunoglobulin-like (Ig) domains, a single juxtamembrane domain (JMD), a cytoplasmic tyrosine kinase domain, Binding of SCF R to its ligand (stem cell factor, SCF) induces receptor dimerization, trans autophosphorylation of the kinase domain, recruitment of signaling proteins via phosphotyrosine binding or Src homology 2 (SH2) domains.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	56.76 kDa
Note	仅供科研使用

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