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Recombinant Human CD84 Protein, His Tag

Recombinant Human CD84 Protein, His Tag

Product Number

KMH249

Alias

LY9B, hCD84, mCD84, SLAMF5, CD84 molecule

Specifications
  • 50ug
  • 100ug
Product Description
AliasLY9B, hCD84, mCD84, SLAMF5, CD84 molecule
Catalog NumberKMH249
Molecular NameCD84
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyCD molecule
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundHuman CD83 is a 4-5 kDa member of the Siglec (or sialic-acid-binding immunoglobulin-like lectin) family of transmembrane proteins. CD83 is a primary marker for dendritic cells. It is also found on B cells, neutrophils, monocytes and macrophages. Except for dendritic cells, CD83 expression is often transient. CD83 binds to sialic acids on target cells. Membrane CD83 promotes T cell proliferation, particularly of CD8+ cytotoxic T cells. Soluble CD83 is immunosuppressive and blocks T cell activation. On monocytes, CD83 is suggested to drive monocytes into a fibrocyte phenotype. A lack of membrane-expressed CD83 leads to an unusual IL-4/IL-1 producing CD4+ T cell phenotype.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight24.75 kDa
Note仅供科研使用

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