Recombinant Human SIAE Protein, His Tag

Name: Recombinant Human SIAE Protein, His Tag
Brand: KMD Bioscience
SKU: KMH1719

KMH1719

LSE, AIS6, CSEC, YSG2, CSE C, sialic acid acetylesterase

DATASHEET MSDS

Product Description

Alias	LSE, AIS6, CSEC, YSG2, CSE C, sialic acid acetylesterase
Catalog Number	KMH1719
Molecular Name	SIAE
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Sialate O-Acetylesterase (SIAE) belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. SIAE is widely expressed with high expression levels in the testis, prostate, and colon. SIAE catalyzes N-acetyl-O-acetylneuraminate and H2O to N-acetylneuraminate and acetate. SIAE removes O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. SIAE down-regulates B lymphocyte antigen receptor signaling (involving CD22), and is required for immunological tolerance. Loss of function mutations in SIAE are much more frequently found in humans with autoimmune diseases especially rheumatoid arthritis and type 1 diabetes.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	55 kDa
Note	仅供科研使用

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