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Recombinant Human MMP-3 Protein, His Tag

Recombinant Human MMP-3 Protein, His Tag

Product Number

KMH1408

Alias

SL 1, STMY, STR1, CHDS6, MMP 3, STMY1, matrix metallopeptidase 3

Specifications
  • 50ug
  • 100ug
Product Description
AliasSL 1, STMY, STR1, CHDS6, MMP 3, STMY1, matrix metallopeptidase 3
Catalog NumberKMH1408
Molecular NameMMP3
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundMMP-3 enzyme is also known as Stromelysin-1or as Transin-1 which hydrolyzes natural collagen at physiological pH and temperature. It dissolves the intervertebral nucleus pulposus and annulus fibrosus of Herniated Lumbar Intervertebral Disk. MMP-3 hydrolyzes components of the extracellular matrix like proteoglycan, laminin, fibronectin, gelatin and collagen types III, IV and IX. It also activates pro-MMP-9 and pro-MMP-8 and superactivates plasmin activated MMP-1. MMP-3 is secreted as a latent proenzyme and is activated by a variety of proteinases, e.g. plasmin, trypsin, chymotrypsin, cathepsin G or human neutrophil elastase. MMP-3 was found to be capable of activating the precursor of IL1-beta.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight50.6 kDa
Note仅供科研使用

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