Recombinant Human MECP2 Protein, His Tag

Name: Recombinant Human MECP2 Protein, His Tag
Brand: KMD Bioscience
SKU: KMH1390

KMH1390

RS, RTS, RTT, PPMX, MRX16, MRX79, MRXSL, AUTSX3, MRXS13, methyl CpG binding protein 2

DATASHEET MSDS

Product Description

Alias	RS, RTS, RTT, PPMX, MRX16, MRX79, MRXSL, AUTSX3, MRXS13, methyl CpG binding protein 2
Catalog Number	KMH1390
Molecular Name	MECP2
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	53.46 kDa
Note	仅供科研使用

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