Recombinant Human MAN1B1 Protein, His Tag

Name: Recombinant Human MAN1B1 Protein, His Tag
Brand: KMD Bioscience
SKU: KMH1373

KMH1373

MRT15, ERMAN1, ERManI, MANA ER, mannosidase alpha class 1B member 1

DATASHEET MSDS

Product Description

Alias	MRT15, ERMAN1, ERManI, MANA ER, mannosidase alpha class 1B member 1
Catalog Number	KMH1373
Molecular Name	MAN1B1
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Endoplasmic Reticulum Mannosyl-Oligosaccharide 1, 2-α-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. MAB1B1 can be inhibited by both 1-deoxymannojirimycin (dMNJ) and kifunensine. Defects in MAN1B1 are the cause of mental retardation autosomal recessive type 15 (MRT15). Mental retardation is characterized by significantly below average general intellectual functioning, it is also associated with impairments in adaptative behavior and manifested during the developmental period.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	65.34 kDa
Note	仅供科研使用

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