Recombinant Human EPHB1 Protein, His Tag

Name: Recombinant Human EPHB1 Protein, His Tag
Brand: KMD Bioscience
SKU: KMH1037

KMH1037

ELK, NET, Hek6, EPHT2, EPH receptor B1

DATASHEET MSDS

Product Description

Alias	ELK, NET, Hek6, EPHT2, EPH receptor B1
Catalog Number	KMH1037
Molecular Name	EPHB1
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	EPHB1 is a member of the Eph family of receptor tyrosine kinases. Ligand-activated EPHB1 forms a signaling complex with Nck, paxillin, and focal adhesion kinase and induces tyrosine phosphorylation of paxillin in a c-Src-dependent manner to promote cell migration. In addition, activated EPHB1 recruits the adaptor proteins Grb2 and p52Shc and promotes p52Shc and c-Src tyrosine phosphorylation as well as MAPK/extracellular signal-regulated kinase (ERK) activation. Expression of dominant-negative c-Src significantly reduced EPHB1-dependent ERK1/2 activation and chemotaxis.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	46.31 kDa
Note	仅供科研使用

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