Human CCL5 Protein, His Tag, Mucin Tag

Name: Human CCL5 Protein, His Tag, Mucin Tag
Brand: KMD Bioscience
SKU: KMP2780

Product Number

KMP2780

Alias

C-C基序趋化因子-5, Human CCL5 Protein, His Tag, mucin Tag, CCL5

Specifications

50ug
100ug
200ug

DATASHEET MSDS

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Product Description

Alias	C-C基序趋化因子-5, Human CCL5 Protein, His Tag, mucin Tag, CCL5
Catalog Number	KMP2780
Product Description	The Human CCL5 Protein(KMP2780) is produced in HEK293 Cells. The target gene encoding the human RANTES (NP_002976.2) (Met 1-Ser 91) is fused with a C-terminal human Fractalkine mucin-stalk (Phe 103-Gln 341) followed by a polyhistidine tag.
Molecular Name	CCL5
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 5(CCL5) is chemotactic for T cells, basophils and eosinophils. Chemokin ligand 5(CCL5) has been considered a HIV-supressor secreted by CD8+ T cells and other immune cells. Chemokin ligand 5(CCL5) is a key to activating recruit leukocytes into inflammatory sites and in the presence of particular cytokines released by T cells, it can change the NK cells into CHAK cells.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	34 kDa

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Human CCL5 Protein, His Tag, Mucin Tag

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