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Human MIP-5 Protein, His Tag

Human MIP-5 Protein, His Tag

Product Number

KMP2777

Alias

巨噬细胞炎症蛋白, Human MIP-5 Protein, His Tag, MIP-5

Specifications
  • 50ug
  • 100ug
  • 200ug
Product Description
Alias巨噬细胞炎症蛋白, Human MIP-5 Protein, His Tag, MIP-5
Catalog NumberKMP2777
Product DescriptionThe Human MIP-5 Protein(KMP2777) is produced in E. coli. The target gene encoding the mature form of human CCL15 (Q16663-1) (Gln 22-Ile 113) is expressed, with a polyHistide tag at the C-terminus.
Molecular NameMIP-5
SpeciesHuman
HostE. coli
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundChemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 15 (CCL15), also known as leukotactin-1, MIP5, MIP1 and HCC-2, is a small cytokine belonging to the C-C chemokine family. CCL15 is prevantly expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. It is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors like CCR1 and CCR3.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight11.7 kDa

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