Human EPOR Protein, His Tag
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Product Number
KMP2714
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Alias
钙黏蛋白E, Human EPOR Protein, His Tag, EPOR
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 钙黏蛋白E, Human EPOR Protein, His Tag, EPOR |
| Catalog Number | KMP2714 |
| Product Description | The Human EPOR Protein(KMP2714) is produced in HEK293 Cells. The target gene encoding the extracellular domain (Met1-Pro250) of human EPOR (NP_000112.1) is fused with a polyhistidine tag at the C-terminus. The purified protein is biotinylated in vitro. |
| Molecular Name | EPOR |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type â… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 26.3 kDa |
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