Human SOST Protein, His Tag

Name: Human SOST Protein, His Tag
Brand: KMD Bioscience
SKU: KMP2660

KMP2660

硬化蛋白, Human SOST Protein, His Tag, SOST

DATASHEET MSDS

Product Description

Alias	硬化蛋白, Human SOST Protein, His Tag, SOST
Catalog Number	KMP2660
Product Description	The Human SOST Protein(KMP2660) is produced in HEK293 Cells. The target gene encoding the SOST (NP_079513.1) (Gln24-Tyr213) is expressed with a polyhistidine tag at the N-terminus. The purified protein is biotinylated in vitro.
Molecular Name	SOST
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS
Background	Sclerostin, the protein product of the SOST gene, is a potent inhibitor of bone formation. Sclerostin protein is widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteeoblasts differentiated for 21 days, and was originally identified as an important regulator of bone remodeling, homeostasis, and links bone resorption and bone apposition. Recent studies have revealed that Sclerostin protein inhibits the bone growth probably by binding to the extracellular domain of the Wnt coreceptors LRP5 and LRP6 and disrupting Wnt-induced Frizzled-LRP complex formation.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	22.5 kDa

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