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Recombinant Human Fibronectin Protein

Recombinant Human Fibronectin Protein

Product Number

KRP700

Alias

FN, FN1, Fibronectin, Cold-insoluble globulin, CIG

Specifications
  • 100ug
  • 500ug
  • 1mg
Product Description
AliasFN, FN1, Fibronectin, Cold-insoluble globulin, CIG
Catalog NumberKRP700
Product IntroductionRecombinant human fibronectin is a key extracellular matrix protein that supports cell adhesion, migration, and tissue structure. Suitable for cell adhesion culture support, wound healing research, and tissue engineering scaffold coating.
Molecular NameFN1
SpeciesHuman
HostSf9 Cells
Size100ug,500ug,1mg
Purity>95%, determined by SDS-PAGE.
ConcentrationContact the sales manager to obtain the concentration of the latest batch.
PurificationAffinity Purification
Endotoxin<0.1 EU/μg, determined by LAL method.
BackgroundA high molecular weight extracellular matrix glycoprotein that mediates cell adhesion, migration, growth, and differentiation through its integrin-binding domains, playing a core role in embryonic development, wound healing, thrombosis, and tumor metastasis.
ApplicationWB, ELISA
Predicted Molecular Weight207 kDa
ReconstitutionIt is recommended that the lyophilized human Fibronectin protein be dissolved in sterile water at a concentration of 100 μg/ml for further dilution as the working concentration.
Storage ConditionSamples are stable for up to twelve months from date of receipt at -20℃ to -104℃. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
StabilityRepeated freezing and thawing is not recommended.
Molecular Weight180­250 kDa
Uniprot IDP02751
References1. Mao, Y. and J.E. Schwarzbauer (2005) Matrix Biol. 24:389. 2. Potts, J.R. and  I.D. Campbell (1996) Matrix Biol. 15:313.  3. Bernard, M.P. et al. (1985) Biochemistry 24:2698.  4. Kornblihtt, A.R. et al. (1983) Proc. Natl. Acad. Sci. USA 80:3218.  5. Kornblihtt, A.R. et al. (1985) EMBO J. 4:1755.  6. Mould, A.P. et al. (1991) J. Biol. Chem. 266:3579.  7. Abe, Y. et al. (2005) Biochem. Biophys. Res. Commun. 338:1640.  8. Altroff, H. et al. (2004) J. Biol. Chem. 279:55995.
FunctionRecombinant human fibronectin is a key extracellular matrix protein that is essential for cell adhesion, migration, and tissue structural support. It is suitable for cell attachment culture support, wound healing research, and tissue engineering scaffold coating.
Product DeclarationThis product is for research use only and must not be used directly on the human body or for injection.
Temperature RangeStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -44℃. Avoid repeated freeze-thaw cycles.
Product Full NameRecombinant Human Fibronectin Protein
TargetFibronectin
FAQ
  • What is fibronectin?

    An important extracellular matrix glycoprotein that provides adhesion sites for cells, mediating cell adhesion, spreading, migration, and signal transduction.

  • How is it used in stem cell culture?

    It is widely used as a cell adhesion matrix in feeder-free cultures, for the culture of pluripotent stem cells, hematopoietic stem cells, mesenchymal stem cells, etc., providing physical support and integrin-mediated biological signals.

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