Recombinant Human IL-11 Protein
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Product Number
KRP698
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Alias
IL-11,Interleukin-11,IL11,Adipogenesis inhibitory factor
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Specifications
- 100ug
- 500ug
- 1mg
Product Description
| Alias | IL-11,Interleukin-11,IL11,Adipogenesis inhibitory factor |
| Catalog Number | KRP698 |
| Product Introduction | Recombinant human interleukin-11 is an important cytokine that promotes platelet production and mucosal protection. Commonly used in platelet generation research, intestinal mucosal protection experiments, and bone marrow suppression models after chemotherapy. |
| Molecular Name | IL11 |
| Species | Human |
| Host | Sf9 Cells |
| Size | 100ug,500ug,1mg |
| Purity | >95%, determined by SDS-PAGE. |
| Concentration | Contact the sales manager to obtain the concentration of the latest batch. |
| Purification | Affinity Purification |
| Endotoxin | <0.1 EU/μg, determined by LAL method. |
| Background | A multifunctional cytokine that can stimulate hematopoiesis, promote acute-phase protein production, and participate in bone metabolism and gastrointestinal mucosal protection. |
| Application | WB, ELISA |
| Predicted Molecular Weight | 19 kDa |
| Reconstitution | It is recommended that the lyophilized human IL-11 protein be dissolved in PBS at a concentration of 100 μg/ml for further dilution as the working concentration. |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -102℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Repeated freezing and thawing is not recommended. |
| Molecular Weight | 20 kDa |
| Uniprot ID | P20809 |
| References | 1. Putoczki, T. and M. Ernst (2010) J. Leukoc. Biol. 88:1109. 2. Paul, S.R. et al. (1990) Proc. Natl. Acad. Sci. USA 87:7512. 3. Kawashima, I. et al. (1991) FEBS Lett. 283:199. 4. Barton, V.A. et al. (2000) J. Biol. Chem. 275:36197. 5. Curtis, D.J. et al. (1997) Blood 90:4403. 6. Baumann, H. et al. (1996) J. Immunol. 157:284. 7. Karow, J. et al. (1996) Biochem. J. 318:489. |
| Function | Recombinant human interleukin-11 is an important cytokine that promotes platelet production and mucosal protection. It is commonly used for platelet production research, intestinal mucosal protection experiments, and chemotherapy-induced bone marrow suppression models. |
| Product Declaration | This product is for research use only and must not be used directly on the human body or for injection. |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -42℃. Avoid repeated freeze-thaw cycles. |
| Product Full Name | Recombinant Human IL-11 Protein |
| Target | IL-11 |
FAQ
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Which family does IL-11 belong to? What are its main functions?
It belongs to the IL-6 family of cytokines, and its main functions include promoting hematopoiesis (especially megakaryocyte maturation) and participating in the process of embryo implantation.
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What are its applications in stem cell culture?
It is mainly used to promote the generation of megakaryocytes and platelets; some studies have shown that it can promote the growth of certain organoids (such as intestines); in mouse embryonic stem cells, it can partially replace the function of LIF.
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