Recombinant Mouse Noggin Protein, C-10*His tag
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Product Number
KRP364
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Alias
Noggin,NOG,SYM1,SYNS1,SYNS1A
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Specifications
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
Product Description
| Alias | Noggin,NOG,SYM1,SYNS1,SYNS1A |
| Catalog Number | KRP364 |
| Product Introduction | Noggin is a secreted protein that precisely regulates cell differentiation and tissue morphogenesis during embryonic development by binding to and inhibiting bone morphogenetic proteins (BMP). |
| Expression System | HEK293F Cells |
| Product Description | Mouse Nog(20-232 aa) |
| Molecular Name | NOG |
| Species | Mouse |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Purity | ≥90% |
| Concentration | Contact the sales manager to obtain the concentration of the latest batch. |
| Purification | Affinity Purification |
| Endotoxin | < 0.1 EU per ug |
| Formulation | Supplied in PBS |
| Background | Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite (PubMed:9585504, PubMed:9603738). Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (By similarity). {ECO:0000250|UniProtKB:Q13253, ECO:0000269|PubMed:9585504, ECO:0000269|PubMed:9603738}. |
| Biological Activity | Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 forthis effect is 0.06-0.3 µg/mL in the presence of 50 ng/mL of Recombinant Human BMP-4. |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Molecular Weight | 30-35 kDa |
| Uniprot ID | P97466 |
| Product Declaration | This product is for research use only and must not be used directly on the human body or for injection. |
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