KMH1083
Acidic Fibroblast Growth Factor(AFGF), AFGF, ECGF, FGFA, ECGFA, ECGFB, FGF 1, HBGF1, HBGF 1, GLIO703, ECGF beta, FGF alpha, fibroblast growth factor 1
| Alias | Acidic Fibroblast Growth Factor(AFGF), AFGF, ECGF, FGFA, ECGFA, ECGFB, FGF 1, HBGF1, HBGF 1, GLIO703, ECGF beta, FGF alpha, fibroblast growth factor 1 |
| Catalog Number | KMH1083 |
| Molecular Name | FGF1 |
| Species | Human |
| Host | E.coli |
| Size | 50ug, 500ug, 1mg |
| Purity | >95% as determined by reducing SDS-PAGE |
| Endotoxin | Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Background | FGF acidic, also known as ECGF, FGF-1and HBGF-1, is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. It is a mitogenic peptide that is produced by multiple cell types and stimulates the proliferation of cells of mesodermal, ectodermal, and endodermal origin. Its association with heparan sulfate is a prerequisite for activation of FGF receptors. Internalized FGF acidic migrates to the nucleus where it is phosphorylated by nuclear PKC delta, exported to the cytosol, dephosphorylated, and degraded. Intracellular FGF acidic inhibits p53 activity and proapoptotic signaling. |
| Application | SDS-PAGE, WB, ELISA |
| Tag | No Tag |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
| Sequence | AEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDR SDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLER LEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD |
| Molecular Weight | 17.3 KDa |
| Uniprot ID | P05230 |
| Note | For Research Use Only! |
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