Recombinant Human SMAD1 Protein, Gst Tag

Name: Recombinant Human SMAD1 Protein, Gst Tag
Brand: KMD Bioscience
SKU: KMH1730

KMH1730

BSP1, JV41, BSP 1, JV4 1, MADH1, MADR1, SMAD family member 1

DATASHEET MSDS

Product Description

Alias	BSP1, JV41, BSP 1, JV4 1, MADH1, MADR1, SMAD family member 1
Catalog Number	KMH1730
Molecular Name	SMAD1
Species	Human
Host	E. coli
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	Please contact our customer service for more information.
Formulation	PBS
Background	SMAD1 is a member of the SMAD family which are signal transducers and transcriptional modulators that mediate multiple signaling pathways. The actions of bone morphogenetic proteins (BMPs) are mediated by SMAD1 and SMAD1 can be phosphorylated and activated by the BMP receptor kinase. Phosphorylated SMAD1 forms a complex with SMAD4 that is important for its function in the transcription regulation. The SMAD1-SMAD4 complex is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. The formation of a complex between STAT3 and SMAD1, bridged by p3, is involved in the cooperative signaling of LIF and BMP2 and the subsequent induction of astrocytes from neuronal progenitors.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	77.15 kDa
Note	仅供科研使用

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