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Recombinant E. coli Mug Protein, No Tag

Recombinant E. coli Mug Protein, No Tag

Product Number

PO143

Alias

ECK3058, ygjF, stationary phase mismatch/uracil DNA glycosylase

Specifications
  • 50ug
  • 100ug
Product Description
AliasECK3058, ygjF, stationary phase mismatch/uracil DNA glycosylase
Catalog NumberPO143
Molecular Namemug
SpeciesE. coli (strain K12)
HostE. coli
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
EndotoxinPlease contact our customer service for more information.
FormulationPBS
BackgroundG/U mismatch-specific DNA glycosylase, xanthine DNA glycosylase, also known as mug, belongs to the TDG/mug DNA glycosylase family. It has been proposed that the Mug protein excises 3, N4-ethenocytosine and removes the uracil base from mismatches in the order of U:G>U:A, although the biological role remains unclear. The enzyme Uracil-N-Glycosylase removes uracil from the DNA leaving an AP site. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Recombinant E.coli mug protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight18.59 kDa
Note仅供科研使用

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