Recombinant Mouse IL-18bp Protein, Fc Tag

Name: Recombinant Mouse IL-18bp Protein, Fc Tag
Brand: KMD Bioscience
SKU: MOP2205

MOP2205

MC54L, Igifbp, IL 18BP, interleukin 18 binding protein

DATASHEET MSDS

Product Description

Alias	MC54L, Igifbp, IL 18BP, interleukin 18 binding protein
Catalog Number	MOP2205
Molecular Name	Il18bp
Species	Mouse
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Mouse IL-18BP is a circulating glycoprotein, which functions as an IL-18 antagonist by binding to IL-18 with high affinity and neutralizing its biological activity. IL-18BP has no amino acid sequence homology to IL-18 or IL-1 receptors. The gene for human IL-18BP encodes at least four isoforms by alternative splicing. The IL-18BP isoforms A and C each contain one immunoglobulin (Ig)-like C2-type domain while isoforms B and D lack the complete Ig domain. The complete Ig domain has been shown to be essential for IL-18BPs binding and neutralizing properties. Several poxviruses have been shown to encode proteins with sequence similarity to human and mouse IL-18BPs that also bind and inhibit IL-18 bioactivities. This could lead to viral modulation of host immune responses.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	43.15 kDa
Note	仅供科研使用

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