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Recombinant Human GFRA2 Protein, His Tag

Recombinant Human GFRA2 Protein, His Tag

Product Number

KMH1162

Alias

NTNRA, RETL2, TRNR2, GDNFRB, NRTNR ALPHA, GDNF family receptor alpha 2

Specifications
  • 50ug
  • 100ug
Product Description
AliasNTNRA, RETL2, TRNR2, GDNFRB, NRTNR ALPHA, GDNF family receptor alpha 2
Catalog NumberKMH1162
Molecular NameGFRA2
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundGlial cell line-derived neurotrophic factor family receptor alpha-2, also known as GFRA2, is the cognate co-receptor for the neurotrophic factor neurturin that is selectively expressed by isolectin B(4) (IB 4)-binding nociceptive sensory neurons. GFRA2 is required for the development of the myenteric nerve plexus and is an excellent candidate gene for Hirschsprung disease (HSCR). GFRalpha2 signaling is also needed for development of the parasympathetic islet innervation that is critical for vagally induced hormone secretion.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight46.2 kDa
Note仅供科研使用

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