KMH1071
CD16, FCG3, CD16A, FCGR3, IGFR3, IMD20, FCR 10, FCRIII, FCGRIII, FCRIIIA, Fc fragment of IgG receptor IIIa
| Alias | CD16, FCG3, CD16A, FCGR3, IGFR3, IMD20, FCR 10, FCRIII, FCGRIII, FCRIIIA, Fc fragment of IgG receptor IIIa |
| Catalog Number | KMH1071 |
| Molecular Name | FCGR3A |
| Species | Human |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | Other protein |
| Purity | ≥90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | PBS |
| Background | Receptors for the Fc region of immunoglobin G (Fcγ R) are divided into three classes and CD16 (Fcγ RIII) is a multifunctional, low/intermediate affinity receptor. In human, CD16 is expressed as two distinct forms (CD16a and CD16b) encoded by two different highly homologous genes in a cell type-specific manner. CD16b is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas CD16a is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed by a subset of T lymphocytes, natural killer (NK) cells, monocytes, and macrophages. CD16a has an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and delivers an activation signal in the immune responses. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Molecular Weight | 21.12 kDa |
| Note | 仅供科研使用 |
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