Recombinant Human Clusterin/CLU Protein, His Tag

Name: Recombinant Human Clusterin/CLU Protein, His Tag
Brand: KMD Bioscience
SKU: KMH893

KMH893

CLI, AAG4, APOJ, CLU1, CLU2, KUB1, SGP2, APO J, SGP 2, SP 40, TRPM2, TRPM 2, NA1/NA2, clusterin

DATASHEET MSDS

Product Description

Alias	CLI, AAG4, APOJ, CLU1, CLU2, KUB1, SGP2, APO J, SGP 2, SP 40, TRPM2, TRPM 2, NA1/NA2, clusterin
Catalog Number	KMH893
Molecular Name	CLU
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Clusterin mRNA and Clusterin protein are shown to increase with androgen treatment. Binding of clusterin to the LDL-Receptor plays a role in the pathogenesis of membranous glomerulonephritis. Clusterin is down regulated in CaP in association with matched benign controls. Clusterin is involved in cellular senescence and tumorigenesis. Clusterin is involved in photo-oxidative cell death pathway. Clusterin is a functional tumor marker for the diagnosis of pediatric large cell lymphoma. Clusterin is activated in low pH. Clusterin is involved in the inhibition of NF-kappaB signaling through stabilization of IkappaBs thus results in suppression of tumor cell motility. N-terminal deletion of clusterin is vital for its alterations of biogenesis in esophageal squamous cell carcinoma.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	46.97 kDa
Note	仅供科研使用

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