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Recombinant Human CD272/BTLA Protein, His Tag

Recombinant Human CD272/BTLA Protein, His Tag

Product Number

KMH421

Alias

BTLA1, CD272, B and T lymphocyte associated

Specifications
  • 50ug
  • 100ug
Product Description
AliasBTLA1, CD272, B and T lymphocyte associated
Catalog NumberKMH421
Molecular NameBTLA
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyCD molecule
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationSupplied as solution form in 50 mM Tris-HCl, pH 8.0, 150 mM NaCl./Lyophilized from 50 mM Tris-HCl, pH 8.0, 150 mM NaCl.
BackgroundBTK (also known as Bruton tyrosine kinase) plays a crucial role in B-lymphocyte differentiation and activation. BTK interacts with SRC homology 3 domains of FYN, LYN and HCK that are activated upon stimulation of B- and T-cell receptors. Defects in the BTK gene cause Agammaglobulinemia, an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement. The unique role of BTK makes it a desirable target for potential anti-cancer, anti-inflammatory and anti-viral agents as well as other treatments.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight14.68 kDa
Note仅供科研使用

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