Recombinant Human CD266/TNFRSF12A Protein, Fc Tag

Name: Recombinant Human CD266/TNFRSF12A Protein, Fc Tag
Brand: KMD Bioscience
SKU: KMH415

KMH415

FN14, CD266, TWEAKR, TNF receptor superfamily member 12A

DATASHEET MSDS

Product Description

Alias	FN14, CD266, TWEAKR, TNF receptor superfamily member 12A
Catalog Number	KMH415
Molecular Name	TNFRSF12A
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	CD molecule
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	TNFSF12 is a cytokine that is part of the TNF ligand family. TNFSF12 is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue distribution. TNFSF12 induces apoptosis through multiple pathways of cell death in a cell type-specific manner. TNFSF12 promotes proliferation and migration of endothelial cells, and therefore acts as a regulator of angiogenesis. TNFSF12 is expressed in adult heart, pancreas, skeletal muscle, small intestine, spleen and peripheral blood lymphocytes. TWEAK h induces NFkB and chemokine secretion. TNFSF12 exerts an apoptotic activity in HT-29 human adenocarcinoma cells whilst cultured in the presence of IFN. TNFSF12 promotes proliferation and migration of endothelial cells.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	30.72 kDa
Note	仅供科研使用

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