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Recombinant Human CD178/FASLG Protein, His Tag

Recombinant Human CD178/FASLG Protein, His Tag

Product Number

KMH360

Alias

APTL, FASL, CD178, CD95L, ALPS1B, CD95 L, TNFSF6, TNLG1A, APT1LG1, Fas ligand

Specifications
  • 50ug
  • 100ug
Product Description
AliasAPTL, FASL, CD178, CD95L, ALPS1B, CD95 L, TNFSF6, TNLG1A, APT1LG1, Fas ligand
Catalog NumberKMH360
Molecular NameFASLG
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyCD molecule
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundFas ligand (FasL) is a type II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Fas ligand is a homotrimeric protein and signals through trimerization of FasR, which spans the membrane of the target cell. This trimerization usually leads to apoptosis, or cell death. Soluble Fas ligand is generated by cleaving membrane-bound FasL at a conserved cleavage site by the external serine matrix metalloproteinase MMP-7. Soluble FasL is less active than their membrane-bound counterparts and do not induce receptor trimerization and DISC formation. FasL is regarded as a potential target for immunotherapy.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight16.28 kDa
Note仅供科研使用

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