KMH337
KIR G1, NKAT10, CD158E2, NKAT 10, KIR 123FM, killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1
| Alias | KIR G1, NKAT10, CD158E2, NKAT 10, KIR 123FM, killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1 |
| Catalog Number | KMH337 |
| Molecular Name | KIR3DS1 |
| Species | Human |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | CD molecule |
| Purity | ≥90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | PBS |
| Background | KIR3DS1(3DS1, CD158e2) is a type I transmembrane protein that belongs to the killercell Ig-like receptor (KIR) family. KIRs are expressed on CD56 dim NK cellsand T cell subsets where they differentiate normal from abnormal cells, and regulateeffector functions in the innate immune system. KIRs are named for the numberof Ig-like domains (2D or 3D) in the extracellular domain(ECD), and whether theyhave long or short (L, S) cytoplasmic tails. Like other activating KIRs, KIR3DS1has a short cytoplasmic tail and a positively charged amino acid (aa) withinthe transmembrane domain that interacts with the ITAM-bearing signalingadaptor, DAP12. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Molecular Weight | 37.4 kDa |
| Note | 仅供科研使用 |
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