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Recombinant Human IL25 Protein, His Tag

Recombinant Human IL25 Protein, His Tag

Product Number

KMH137

Alias

IL17E, interleukin 25

Specifications
  • 50ug
  • 100ug
Product Description
AliasIL17E, interleukin 25
Catalog NumberKMH137
Molecular NameIL25
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyInterleukin
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundIL-25 also called IL-17E cytokine has a sequence similarity with IL17. IL-17E indluces NF-kappaB activation, and stimulates the production of IL-8. IL17E and IL17B are ligands for the cytokine receptor IL17BR. IL-25 is a proinflammatory cytokine favoring Th2-type immune response. The upregulation of costimulation-induced IL-17E receptors and release of cytokines and chemokines from IL-17E treated costimulated Th cells are differentially regulated by intracellular JNK, p38 MAPK and NF-kappaB activity. Blocking Iinterleukin-25 prevents airway hyperresponsiveness, a critical feature of clinical asthma.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight19.47 kDa
Note仅供科研使用

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