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Recombinant Human IL8/CXCL8 Protein, Fc Tag

Recombinant Human IL8/CXCL8 Protein, Fc Tag

Product Number

KMH119

Alias

IL8, NAF, GCP1, LECT, LUCT, NAP1, GCP 1, LYNAP, MDNCF, MONAP, NAP 1, SCYB8, C X C motif chemokine ligand 8

Specifications
  • 50ug
  • 100ug
Product Description
AliasIL8, NAF, GCP1, LECT, LUCT, NAP1, GCP 1, LYNAP, MDNCF, MONAP, NAP 1, SCYB8, C X C motif chemokine ligand 8
Catalog NumberKMH119
Molecular NameCXCL8
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyInterleukin
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS, pH7.5
BackgroundIL-8 is a member of the alpha (CXC) subfamily of chemokines, which also includes platelet factor 4, GRO, IP1, etc. IL-8 is a potent chemoattractant for neutrophils. In addition, IL-8 also has a wide range of other proinflammatory effects. IL-8 causes degranulation of neutrophil specific granules and azurophilic granules. IL-8 induces expression of the cell adhesion molecules CD11/CD18 and enhances the adherence of neutrophils to endothelial cells and subendothelial matrix proteins. Besides neutrophils, IL-8 is also chemotactic for basophils, T cells and eosinophils. IL-8 has been reported to be a comitogen for keratinocytes and was also shown to be an autocrine growth factor for melanoma cells. IL-8 was also reported to be angiogenic both in vivo and in vitro.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight33.58 kDa
Note仅供科研使用

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