Human CD134 Protein, Fc Tag
-
Product Number
KMP2339
-
Alias
肿瘤坏死因子受体超家族成员4, Tumor necrosis factor receptor superfamily member 4, CD134
-
Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 肿瘤坏死因子受体超家族成员4, Tumor necrosis factor receptor superfamily member 4, CD134 |
| Catalog Number | KMP2339 |
| Product Description | The Human CD134 Protein(KMP2339) is produced in HEK293 Cells and the target gene encoding Leu29-Ala216 is expressed with a Fc tag at the N-terminus. |
| Molecular Name | CD134 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand(OX40L) will occur when activated T cells bind to professional antigen-presenting cells(APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases. |
| SDS-PAGE | |
| Predicted Molecular Weight | 20.16 kDa |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
| Uniprot ID | Q6FGS4 |
- Protein Platform
- Protein Expression Services
- Protein Modification & Detection Services
- Protein Interaction Services
- Protein Purification Service
- Antibody Discovery Platform
- VHH Antibody Platform
- Phage Display Platform
- Antibody Humanization Platform
- Single B Cell Screening Platform
- Antibody Expression & Validation Platform
- Peptide Library Platform
- Custom Antibody Platform
- Innovative Drug Discovery Platform
- Product Center
- Proteins
- Antibodies
- Raw Materials Reagents
- Small Molecule Reagents
- Peptide Products
- Nanoparticle Products
- Contact Us
- Phone：400-621-6806
- Mobile：13110936064（WeC
- E-mail：[email protected]
- Address：Room 108, Building 10, No. 6 Hechang Road, Wuqing Development Zone, Tianjin City
-
WeChat
-
Service Account
-
400-621-6806 -
3599163699 -
Monday to Friday 9:00-18:00 -
-
0
-
