Human CD226 Protein, His Tag
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Product Number
KMP2308
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Alias
白细胞分化抗原, CD226 antigen, CD226
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 白细胞分化抗原, CD226 antigen, CD226 |
| Catalog Number | KMP2308 |
| Product Description | The Human CD226 Protein(KMP2308) is produced in HEK293 Cells and the target gene encoding Glu19-Asn247 is expressed with a 6His tag at the C-terminus. |
| Molecular Name | CD226 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Human DNAX accessory molecule 1(DNAM-1/CD226) is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily. Mature human DNAM-1 contains an extracellular domain(ECD) with two Ig-like C2-set domains and a cytoplasmic region that contains motifs for binding PDZ domains and band 4.1 family proteins. DNAM-1 is expressed on multiple lymphoid and myeloid cells and interacts with CD155 and CD112. Ligation of DNAM-1 promotes the activation of NK cells, CD8+ T cells, and mast cells, dendritic cell maturation, megakaryocyte and activated platelet adhesion to vascular endothelial cells, and monocyte extravasation; it inhibits the forrmation of osteoclasts. Plateletendothelium, interactions mediated by DNAM-1, enable the metastasis of tumor cells to the lung. |
| SDS-PAGE | |
| Predicted Molecular Weight | 26.83 kDa |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
| Uniprot ID | J3QRQ4 |
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