Cynomolgus TNFRSF17 Protein, His Tag
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Product Number
KMP2241
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Alias
B细胞成熟抗原, CD269, BCMA
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | B细胞成熟抗原, CD269, BCMA |
| Catalog Number | KMP2241 |
| Product Description | The Cynomolgus TNFRSF17 Protein(KMP2241) is produced in HEK293 Cells and the target gene encoding Met1-Ala53 is expressed with a 6His tag at the C-terminus. |
| Molecular Name | TNFRSF17 |
| Species | Cynomolgus |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >85% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | 50mM Tris, 100mM Glycine, pH7.5 |
| Background | B cell maturation antigen(BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF, it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF, members of the TNF ligand superfamily. BCMA expression has been found in immune organs and mature B cell lines. Although some expression has been observed at the cell surface, BCMA appears to be localized to the Golgi compartment. The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells. This data suggests that BCMA may play an important role in B cell development,function and regulation. |
| SDS-PAGE | |
| Predicted Molecular Weight | 6.49 kDa |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
| Uniprot ID | A0A2K5UD97 |
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