Rat DKK1 Protein, His Tag
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Product Number
KMP4272
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Alias
Dickkopf WNT信号通路抑制剂 1, DKK1 Protein, Rat DKK1 Protein, His Tag
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | Dickkopf WNT信号通路抑制剂 1, DKK1 Protein, Rat DKK1 Protein, His Tag |
| Catalog Number | KMP4272 |
| Product Description | The Rat DKK1 Protein(KMP4272) is produced in HEK293 Cells. A DNA sequence encoding the rat DKK1 (NP_001099820.1) (Met1-His270) is expressed with a polyhistide tag at the C-terminus. |
| Molecular Name | DKK1 |
| Species | Rat |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majority of lung cancers, esophageal squamous cell carcinomas, and hormone-resistant breast cancers, while DKK-1 expression is decreased in malignant melanoma and colorectal cancers. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 27.44 kDa |
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