Rat IL-20 Protein
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Product Number
KMP4229
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Alias
白细胞介素20, IL-20 Protein, Rat IL-20 Protein
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 白细胞介素20, IL-20 Protein, Rat IL-20 Protein |
| Catalog Number | KMP4229 |
| Product Description | The Rat IL-20 Protein(KMP4229) is produced in E. coli. A DNA sequence encoding the rat IL20 (P11762) (Leu25-Leu176) is expressed and purified. |
| Molecular Name | IL-20 |
| Species | Rat |
| Host | E. coli |
| Size | 50ug, 100ug, 200ug |
| Purity | >85% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, 20% Glycerol, pH7.4 |
| Background | IL20/Interleukin-20 belongs to the IL-10 family. It is a cytokine structurally related to interleukin 10. IL20/Interleukin-20 can be detected in skin, trachea, and other tissues. It is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells. It has been shown that interleukin-20 transduces its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. It may be involved in epidermal function and psoriasis. It also regulates the proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. Also, IL20/Interleukin-20 also causes cell expansion of multipotential hematopoietic progenitor cells. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 17.7 kDa |
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