Mouse PIK3IP1 Protein, His Tag
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Product Number
KMP4075
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Alias
磷酸肌醇3激酶相互作用蛋白1, PIK3IP1 Protein, Mouse PIK3IP1 Protein, His Tag
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 磷酸肌醇3激酶相互作用蛋白1, PIK3IP1 Protein, Mouse PIK3IP1 Protein, His Tag |
| Catalog Number | KMP4075 |
| Product Description | The Mouse PIK3IP1 Protein(KMP4075) is produced in HEK293 Cells. A DNA sequence encoding the Mouse Pik3ip1 (NP_835362.2) (Met1-Leu170) is expressed with a polyhistidine tag at the C-terminus. |
| Molecular Name | PIK3IP1 |
| Species | Mouse |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | PIK3IP1 contains 1 kringle domain and is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepatocellular carcinoma. PI3K is a well-known regulator of cell division, motility, metabolism and survival in most cell types. Proper liver function and development highly depend on intact PI3K signal transduction. Aberrant PI3K pathway signaling in the liver is associated with hepatocellular carcinoma. PI3K signaling is involved in the homeostasis of lipid and glucose metabolism. Activation of the PI3K pathway induces lipogenesis and glycogenesis in the liver, since both Akt overexpressing transgenic mice and PTEN knockout mice develop fatty liver and hypoglycemia. PIK3IP1 overexpression can contribute to glucose homeostasis and fatty deposition. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 17.5 kDa |
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