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Mouse Rab2 Protein, His Tag

Mouse Rab2 Protein, His Tag

Product Number

KMP4055

Alias

Ras相关蛋白Rab-2A, Rab2 Protein, Mouse Rab2 Protein, His Tag

Specifications
  • 50ug
  • 100ug
  • 200ug
Product Description
AliasRas相关蛋白Rab-2A, Rab2 Protein, Mouse Rab2 Protein, His Tag
Catalog NumberKMP4055
Product DescriptionThe Mouse Rab2 Protein(KMP4055) is produced in E. coli. A DNA sequence encoding the Mouse Rab2a (NP_067493.1) (Met1-Cys212) is expressed with a polyhistidine tag at the N-terminus.
Molecular NameRab2
SpeciesMouse
HostE. coli
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundRAB2A, a protein essential for ER-to-Golgi transport, is critical in promoting proteolytic activity and 3D invasiveness of breast cancer (BC) cell lines.RAB2A is amplified and elevated in human BC and is a powerful and independent predictor of disease recurrence in BC patients. Thus, RAB2A is a novel trafficking determinant essential for regulation of a mesenchymal invasive program of BC dissemination. At the cellular levels, RAB2A controls both canonical polarized Golgi-to-Plasma membrane trafficking of the junctional protein E-cadherin, and post-endocytic trafficking of the membrane-bound metalloprotease, MT1-MMP.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight25.8 kDa

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