Mouse IL17RB Protein, hFc Tag
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Product Number
KMP4009
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Alias
白介素17受体B, IL17RB Protein, Mouse IL17RB Protein, hFc Tag
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 白介素17受体B, IL17RB Protein, Mouse IL17RB Protein, hFc Tag |
| Catalog Number | KMP4009 |
| Product Description | The Mouse IL17RB Protein(KMP4009) is produced in HEK293 Cells. A DNA sequence encoding the Mouse Il17rb (NP_062529.2) (Met1-Gly286) is expressed with the Fc region of human IgG1 at the C-terminus. |
| Molecular Name | IL17RB |
| Species | Mouse |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >85% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | IL17RB (Interleukin 17 Receptor B) is a Protein Coding gene. IL17RB is the receptor for IL17E, the only member of the IL17 family promoting Th2 reactions. IL17RB is induced on human macrophages by IL4 and enhanced by TGFbeta. Overexpression of IL17RB is associated with poor prognosis and the short survival of breast cancer patients.IL17RB/IL17B signaling triggers a substantial increase in cell growth, proliferation, and migration through the activation of NF-kappaB as well as the up-regulation of the Bcl-2. IL17RB may be the only gene expressed in CD4+ T cells whose transcript measurement is correlated with the variation in IgE level in asthmatics. Diseases associated with IL17RB include Chronic Mucocutaneous Candidiasis and Seborrheic Infantile Dermatitis. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 56.8 kDa |
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