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Feline EGFR Protein, His Tag

Feline EGFR Protein, His Tag

Product Number

KMP3789

Alias

表皮生长因子受体, EGFR Protein, Feline EGFR Protein, His Tag

Specifications
  • 50ug
  • 100ug
  • 200ug
Product Description
Alias表皮生长因子受体, EGFR Protein, Feline EGFR Protein, His Tag
Catalog NumberKMP3789
Product DescriptionThe Feline EGFR Protein(KMP3789) is produced in Insect Cells. A DNA sequence encoding the feline EGFR (A0A337S424) (Leu25-Ser645) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameEGFR
SpeciesFeline
HostInsect Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation20mM Tris, 300mM NaCl, 10% Glycerol, pH8.0
BackgroundAs a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight70.18 kDa

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