Cynomolgus GITR Protein, His Tag

Name: Cynomolgus GITR Protein, His Tag
Brand: KMD Bioscience
SKU: KMP3700

KMP3700

糖皮质激素诱导的肿瘤坏死因子受体相关蛋白, GITR Protein, Cynomolgus GITR Protein, His Tag

DATASHEET MSDS

Product Description

Alias	糖皮质激素诱导的肿瘤坏死因子受体相关蛋白, GITR Protein, Cynomolgus GITR Protein, His Tag
Catalog Number	KMP3700
Product Description	The Cynomolgus GITR Protein(KMP3700) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus TNFRSF18 (XP_005545180.1) (Met1-Glu155) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	GITR
Species	Cynomolgus
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	16.1 kDa

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