Canine Canf4 Protein, His Tag
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Product Number
KMP3632
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Alias
过敏原蛋白Can f 4, Canf4 Protein, Canine Canf4 Protein, His Tag
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 过敏原蛋白Can f 4, Canf4 Protein, Canine Canf4 Protein, His Tag |
| Catalog Number | KMP3632 |
| Product Description | The Canine Canf4 Protein(KMP3632) is produced in HEK293 Cells. A DNA sequence encoding the Canine Canf4 (NP_001177855.1) (Met1-Glu174) is expressed with a polyhistidine tag at the C-terminus. |
| Molecular Name | Canf4 |
| Species | Canine |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >90% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | 50mM Tris, 100mM NaCl, 0.02% Tween80, pH8.0 |
| Background | Dog dander is an important cause of respiratory allergy but its content of allergenic components is still incompletely known. The size and the amino acid composition of the ligand-binding pocket indicate that Can f 4 is capable of binding only relatively small hydrophobic molecules which are different from those that Can f 2 is able to bind. The crystal structure of Can f 4 contained both monomeric and dimeric forms of the allergen, suggesting that Can f 4 is able to form transient (weak) dimers. The existence of transient dimers in solution was confirmed by use of native mass spectrometry. The dimeric structure of Can f 4 is formed when the ends of four β-strands are packed against the same strands from the second monomer. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 19.1 kDa |
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