Human IFN gamma Protein
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Product Number
KMP3580
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Alias
干扰素-γ, Human IFN gamma Protein, IFN gamma
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 干扰素-γ, Human IFN gamma Protein, IFN gamma |
| Catalog Number | KMP3580 |
| Product Description | The Human IFN gamma Protein(KMP3580) is produced in E. coli. The target gene encoding the human IFNG (NP_000610.2) (Gln24-Gln166) is expressed. |
| Molecular Name | IFN gamma |
| Species | Human |
| Host | E. coli |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <5.0 EU/mg determined by the LAL method |
| Formulation | 50mM Tris, pH8.0 |
| Background | IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to hAving antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and tumor control. Aberrant IFN gamma expression is associated with some autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 16.91 kDa |
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