Human IL-15 Protein
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Product Number
KMP3572
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Alias
白细胞介素-15, Human IL-15 Protein, IL-15
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 白细胞介素-15, Human IL-15 Protein, IL-15 |
| Catalog Number | KMP3572 |
| Product Description | The Human IL-15 Protein(KMP3572) is produced in E. coli. The target gene encoding the human IL15 (NP_000576.1) (Asn49-Ser162) is expressed. |
| Molecular Name | IL-15 |
| Species | Human |
| Host | E. coli |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <5.0 EU/mg determined by the LAL method |
| Formulation | 50mM Tris, 200mM NaCl, pH8.0 |
| Background | The protein encoded by the IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietic receptor subunits and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively, spliced transcript variants of this gene have been reported. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 12.8 kDa |
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