Human IL-1 beta Protein
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Product Number
KMP3570
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Alias
白细胞介素-1β, Human IL-1 beta Protein, IL-1 beta
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 白细胞介素-1β, Human IL-1 beta Protein, IL-1 beta |
| Catalog Number | KMP3570 |
| Product Description | The Human IL-1 beta Protein(KMP3570) is produced in E. coli. The target gene encoding the mature form of human IL1B (NP_000567.1) (Ala 117-Ser 269) is expressed with a N-terminal Met. |
| Molecular Name | IL-1 beta |
| Species | Human |
| Host | E. coli |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <5.0 EU/mg determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of a successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc). |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 17.5 kDa |
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