KMP3552
CD8A和CD8B的异二聚体蛋白, Human CD8A & CD8B Heterodimer Protein, Flag Tag, His Tag, CD8A & CD8B Heterodimer
| Alias | CD8A和CD8B的异二聚体蛋白, Human CD8A & CD8B Heterodimer Protein, Flag Tag, His Tag, CD8A & CD8B Heterodimer |
| Catalog Number | KMP3552 |
| Product Description | The Human CD8A & CD8B Heterodimer Protein(KMP3552) is produced in HEK293 Cells. The target gene encoding the human CD8A (NP_001759.3) (Met1-Asp182) is fused with a flag tag at the C-terminus, constructed the plasmid 1; The target gene encoding the human CD8B (NP_004922.1) (Met1-Pro170) is fused with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids are co-expressed and the human CD8A&CD8B heterodimer is purified. |
| Molecular Name | CD8A & CD8B Heterodimer |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | CD8A (CD8 Subunit Alpha) is a Protein Coding gene. Diseases associated with CD8A include Cd8 Deficiency, Familial and Herpes Zoster. Among its related pathways are TCR Signaling (Qiagen) and Network map of SARS-CoV-2 signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and coreceptor activity. CD8B (CD8 Subunit Beta) is a Protein Coding gene. Diseases associated with CD8B include Diffuse Large B-Cell Lymphoma and Uterine Corpus Cancer. Among its related pathways are Infectious disease and Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters. Gene Ontology (GO) annotations related to this gene include coreceptor activity and MHC class I protein binding. An important paralog of this gene is CD8B2. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 44.1 kDa |
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