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Human Integrin alpha 6 beta 4 Protein, Flag Tag, His Tag

Human Integrin alpha 6 beta 4 Protein, Flag Tag, His Tag

Product Number

KMP3549

Alias

整合素 α6β4, Human Integrin alpha 6 beta 4 Protein, Flag Tag, His Tag, Integrin alpha 6 beta 4

Specifications
  • 50ug
  • 100ug
  • 200ug
Product Description
Alias整合素 α6β4, Human Integrin alpha 6 beta 4 Protein, Flag Tag, His Tag, Integrin alpha 6 beta 4
Catalog NumberKMP3549
Product DescriptionThe Human Integrin alpha 6 beta 4 Protein(KMP3549) is produced in HEK293 Cells. The target gene encoding the extracellular domain (Met 1-Ser 1011) of human ITGA6 isoform alpha-6X1B (P23229-3) is fused with a flag tag at the C-terminus, constructed the plasmid 1 ; The target gene encoding the extracellular domain (Met 1-Ser 710) of human ITGB4 (CAA37656.1) is fused with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids are co-expressed and the heterodimer is purified
Molecular NameIntegrin alpha 6 beta 4
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>80% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundITGB4 (Integrin Subunit Beta 4) is a Protein Coding gene. Diseases associated with ITGB4 include Epidermolysis Bullosa, Junctional 5B, With Pyloric Atresia and Epidermolysis Bullosa, Junctional 5A, Intermediate. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Integrin Pathway. Gene Ontology (GO) annotations related to this gene include signaling receptor activity and G protein-coupled receptor binding. An important paralog of this gene is ITGB1.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight196 kDa

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