Human CISD1 Protein, His Tag
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Product Number
KMP3311
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Alias
重组人CDGSH铁硫域1, Human CISD1 Protein, His Tag, CISD1
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 重组人CDGSH铁硫域1, Human CISD1 Protein, His Tag, CISD1 |
| Catalog Number | KMP3311 |
| Product Description | The Human CISD1 Protein(KMP3311) is produced in E. coli. The target gene encoding the human CISD1 (NP_060934.1) (Lys32-Thr108) is expressed with a polyhistidine tag at the N-terminus. |
| Molecular Name | CISD1 |
| Species | Human |
| Host | E. coli |
| Size | 50ug, 100ug, 200ug |
| Purity | >90% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | 20mM Tris, 150mM NaCl, 10% Glycerol |
| Background | Mitochondrial dysfunction is thought to play a significant role in neurodegeneration observed in Parkinson's disease (PD), the loss of mitoNEET (CISD1), an iron-sulfur containing protein that regulates mitochondrial bioenergetics, results in mitochondrial dysfunction and loss of striatal dopamine and tyrosine hydroxylase. CDGSH iron sulfur domain 1 (CISD1, also termed mitoNEET), an iron-containing outer mitochondrial membrane protein, negatively regulates ferroptotic cancer cell death. At the cellular level, CISD1 gene expression increased during human adipocyte differentiation in correlation with adipogenic genes.Thus it is a possible role of CISD1 in obesity-associated dysfunctional adipogenesis in human VAT. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 11.3 kDa |
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