Human Neurofascin Protein, hFc Tag
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Product Number
KMP3272
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Alias
神经束蛋白, Human Neurofascin Protein, hFc Tag, Neurofascin
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 神经束蛋白, Human Neurofascin Protein, hFc Tag, Neurofascin |
| Catalog Number | KMP3272 |
| Product Description | The Human Neurofascin Protein(KMP3272) is produced in HEK293 Cells. The target gene encoding the human NFASC (NP_001005388.2) (Met1-Gln939) is expressed with the Fc region of human IgG1 at the C-terminus. The purified protein is biotinylated in vitro. |
| Molecular Name | Neurofascin |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >90% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | NFASC (Neurofascin, also known as NRCAML, NEDCPMD, and NF) is a Protein Coding gene. 13 alternatively spliced human isoforms have been reported. NFASC belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM family. It contains 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. NFASC links the AIS extracellular matrix to the intracellular cytoskeleton. It is broadly expressed in the brain, kidney, and other tissues. Diseases associated with NFASC include Neurodevelopmental Disorder With Central And Peripheral Motor Dysfunction and Demyelinating Polyneuropathy. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 130 kDa |
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