Human MZB1 Protein, hFc Tag
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Product Number
KMP3269
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Alias
边缘区 B 和 B1 细胞特异性蛋白, Human MZB1 Protein, hFc Tag, MZB1
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 边缘区 B 和 B1 细胞特异性蛋白, Human MZB1 Protein, hFc Tag, MZB1 |
| Catalog Number | KMP3269 |
| Product Description | The Human MZB1 Protein(KMP3269) is produced in HEK293 Cells. The target gene encoding the human MZB1 (NP_057543.2) (Met1-Thr185) is expressed with the Fc region of human IgG1 at the C-terminus. |
| Molecular Name | MZB1 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | MZB1 (Marginal Zone B And B1 Cell Specific Protein, also known as MEDA-7 and pERp1) is a Protein Coding gene. MZB1 is a B-cell-specific and endoplasmic reticulum (ER)-localized protein implicated in antibody secretion and integrin-mediated cell adhesion. MZB1 is important for B cell function as a key regulator of antibody secretion, calcium homeostasis, and adhesion. MZB1 may play a central role in B cell neoplasms and is a potential target for future therapeutic interventions. Low MZB1 expression was an independent prognostic factor for recurrence after curative gastrectomy and was associated significantly with increased hematogenous recurrence. MZB1 acts as a suppressor of gastric cancer (GC). Low MZB1 expression in the primary GC tissue is predictive of recurrence after curative resection. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 44.9 kDa |
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