Human PIG3 Protein, His Tag

Name: Human PIG3 Protein, His Tag
Brand: KMD Bioscience
SKU: KMP3241

KMP3241

肿瘤蛋白 p53 诱导蛋白 3, Human PIG3 Protein, His Tag, PIG3

DATASHEET MSDS

Product Description

Alias	肿瘤蛋白 p53 诱导蛋白 3, Human PIG3 Protein, His Tag, PIG3
Catalog Number	KMP3241
Product Description	The Human PIG3 Protein(KMP3241) is produced in E. coli. The target gene encoding the human TP53I3 (NP_004872.2) (Met1-Gln332) is expressed with a polyhistidine tag at the N-terminus.
Molecular Name	PIG3
Species	Human
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Nutlin-3 variably induces apoptosis and cell cycle arrest in cancer cells while it shows low/absent cytotoxicity in normal cells, Nutlin-3 is a promising anti-cancer agent, which exhibits activity against a variety of cancers, including acute myeloid leukemia (AML). The important role of TP53I3/PIG3 in mediating the apoptotic activity of Nutlin-3 was underlined by knock-down experiments with siRNA specific for TP53I3/PIG3, which resulted in a significant decrease in the pro-apoptotic activity of Nutlin-3.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	37.8 kDa

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