Human AKR1C4 Protein, His Tag

Name: Human AKR1C4 Protein, His Tag
Brand: KMD Bioscience
SKU: KMP3201

KMP3201

醛酮还原酶家族 1 成员 C4, Human AKR1C4 Protein, His Tag, AKR1C4

DATASHEET MSDS

Product Description

Alias	醛酮还原酶家族 1 成员 C4, Human AKR1C4 Protein, His Tag, AKR1C4
Catalog Number	KMP3201
Product Description	The Human AKR1C4 Protein(KMP3201) is produced in E. coli. The target gene encoding the human AKR1C4 (AAH20744.1) (Met1-Tyr323) is expressed with a polyhistidine tag at the N-terminus.
Molecular Name	AKR1C4
Species	Human
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation between the expression levels of these family members and the malignant transformation as well as the resistance to cancer therapy. Type I human hepatic 3alpha-hydroxysteroid dehydrogenase (AKR1C4) plays a significant role in bile acid biosynthesis, steroid hormone metabolism, and xenobiotic metabolism.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	39.4 kDa

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